Identifiers and Description

Gene Model Identifier

Contig13116.g13984

Standard Name

HIS38 (Macronuclear gene encoding histone variant H3.8)

Aliases

H3.8 | mdp64 | protein_X

Description

histone variant H3.8

Genome Browser

Gene Ontology Annotations

Molecular Function

• JUN kinase activity (IEA) | GO:0004705
• basal transcription machinery binding (IEA) | GO:0001098
• secondary active cyanate transmembrane transporter activity (IEA) | GO:0015541
• D-galactose 6-phosphate 1-epimerase activity (IEA) | GO:0102541
• alcohol dehydrogenase (NADP+) activity (IEA) | GO:0008106

Biological Process

• purine nucleotide interconversion (IEA) | GO:0015950
• reproduction (IEA) | GO:0000003
• positive regulation of semaphorin-plexin signaling pathway (IEA) | GO:2001262
• regulation of C-C chemokine binding (IEA) | GO:2001263
• negative regulation of B cell mediated immunity (IEA) | GO:0002713

Domains

No Data fetched for Domains

Gene Expression Profile

Homologs

No Data fetched for Homologs

General Information

Paragraph No	Gene Name	Paragraph Text
10	HIS38	Histone gene HIS38 encoding histone variant H3.8, formerly mdp64 (before 2013). Renamed with respect to: Talbert PB et al. A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin. 2012 Jun 21;5:7. doi: 10.1186/1756-8935-5-7. PubMed PMID: 22650316; PubMed Central PMCID: PMC3380720.
11	HIS38	Possibly indentical to protein X (Schlegel et al (1990) Transcriptionally inactive micronuclei, macronuclear anlagen and transcriptionally active macronuclei differ in histone composition in the hypotrichous ciliateStylonychia lemnae. Chromosoma 99(6) 401-406.)

Associated Literature

1. Ref:24502432: Forcob S, Bulic A, Jönsson F, Lipps HJ, Postberg J (2014) Differential expression of histone H3 genes and selective association of the variant H3.7 with a specific sequence class in Stylonychia macronuclear development. Epigenetics & chromatin 7(1):4

Sequences

>Contig13116.g13984(protein)
MPRQKLAGKKMKSSTKKSVASGSKASKSTMKKKTAPAEGGIKTHNRRFKPGTVALREIKR
YQKVTNLLLLKAPFQRFVRAICEGIDAQLRFQSQALLAVQEAAEMYLVGLFEDSNLCAIH
ANRVTVMKKDMELARRIRGERFHDHRDLQPKNGDEVFYQLPYYNEKEQMAHLKKVIGRN

>Contig13116.g13984(coding)
atgcccagacaaaagctcgccggtaagaagatgaagtcctcaaccaagaagagtgttgcc
tcaggctccaaggccagcaagtcaaccatgaaaaagaagactgctccagctgagggaggt
atcaagacccacaacagaagattcaagccaggtaccgtcgctctcagagagatcaagaga
tactagaaggtcaccaacctcctcctcctcaaggctcccttccagagattcgtcagagcc
atctgcgaaggaatcgacgcccaactcagattctagtcacaagccctcctcgccgtccaa
gaagctgctgagatgtacttggtcggacttttcgaagactccaacttgtgcgccattcac
gccaacagagtgactgtcatgaagaaggacatggagctcgccagaagaatcagaggagag
agattccacgaccacagagacctccaacccaagaatggggatgaagttttctaccagttg
ccctactacaacgagaaggagcagatggctcacctcaagaaagttatcggcagaaactga