Identifiers and Description

Gene Model Identifier

Contig13116.g13984

Standard Name

HIS38 (Macronuclear gene encoding histone variant H3.8)

Aliases

H3.8 | mdp64 | protein_X

Description

histone variant H3.8

Genome Browser

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No Genome Browser Data Present

Gene Ontology Annotations

Molecular Function

• alcohol dehydrogenase (NADP+) activity (IEA) | GO:0008106
• basal transcription machinery binding (IEA) | GO:0001098
• JUN kinase activity (IEA) | GO:0004705
• obsolete D-galactose 6-phosphate 1-epimerase activity (IEA) | GO:0102541
• secondary active cyanate transmembrane transporter activity (IEA) | GO:0015541

Biological Process

• negative regulation of B cell mediated immunity (IEA) | GO:0002713
• obsolete reproduction (IEA) | GO:0000003
• positive regulation of semaphorin-plexin signaling pathway (IEA) | GO:2001262
• purine nucleotide interconversion (IEA) | GO:0015950
• regulation of C-C chemokine binding (IEA) | GO:2001263

Domains

No Data fetched for Domains

Homologs

No Data fetched for Homologs

General Information

No.	Gene Name(s)	Paragraph Text
159	HIS38	Histone gene HIS38 encoding histone variant H3.8, formerly mdp64 (before 2013). Renamed with respect to: Talbert PB et al. A unified phylogeny-based nomenclature for histone variants. Epigenetics Chromatin. 2012 Jun 21;5:7. doi: 10.1186/1756-8935-5-7. PubMed PMID: 22650316; PubMed Central PMCID: PMC3380720.
160	HIS38	Possibly indentical to protein X (Schlegel et al (1990) Transcriptionally inactive micronuclei, macronuclear anlagen and transcriptionally active macronuclei differ in histone composition in the hypotrichous ciliateStylonychia lemnae. Chromosoma 99(6) 401-406.)

Associated Literature

1. Ref:24502432: Forcob S, Bulic A, Jönsson F, Lipps HJ, Postberg J (2014) Differential expression of histone H3 genes and selective association of the variant H3.7 with a specific sequence class in Stylonychia macronuclear development. Epigenetics & chromatin 7(1):4

Sequences

>Contig13116.g13984(coding)
atgcccagacaaaagctcgccggtaagaagatgaagtcctcaaccaagaagagtgttgcc
tcaggctccaaggccagcaagtcaaccatgaaaaagaagactgctccagctgagggaggt
atcaagacccacaacagaagattcaagccaggtaccgtcgctctcagagagatcaagaga
tactagaaggtcaccaacctcctcctcctcaaggctcccttccagagattcgtcagagcc
atctgcgaaggaatcgacgcccaactcagattctagtcacaagccctcctcgccgtccaa
gaagctgctgagatgtacttggtcggacttttcgaagactccaacttgtgcgccattcac
gccaacagagtgactgtcatgaagaaggacatggagctcgccagaagaatcagaggagag
agattccacgaccacagagacctccaacccaagaatggggatgaagttttctaccagttg
ccctactacaacgagaaggagcagatggctcacctcaagaaagttatcggcagaaactga

>Contig13116.g13984(protein)
MPRQKLAGKKMKSSTKKSVASGSKASKSTMKKKTAPAEGGIKTHNRRFKPGTVALREIKR
YQKVTNLLLLKAPFQRFVRAICEGIDAQLRFQSQALLAVQEAAEMYLVGLFEDSNLCAIH
ANRVTVMKKDMELARRIRGERFHDHRDLQPKNGDEVFYQLPYYNEKEQMAHLKKVIGRN